At RCIS 2018, among other regular topics a particular attention will be given to the special topic: “Enterprise of the future”. This theme is intended to explore how Information Science, in terms of methods and tools, can help enterprises and organisations face a wide range of challenges, thanks to the power of Information. Indeed, enterprises need to be able to continually innovate as fast as (or faster than) their highly fluctuating environments and markets. However, complexity of information representation and exploitation, decision-making processes at multiple levels and their important –often unforeseen - effects, drastically impact enterprises agility and innovation. How does Information Science currently influence the future of enterprises and how can it influence it in a more efficient and innovative way? What are the main strategic challenges? How can Information Sciences strengthen and become an unavoidable and fundamental pillar of the Enterprise of the Future?